PUBLICATIONSNeuroDegenerationAGING
septiembre 5, 2023
Carotid Body-Mediated Chemoreflex Function in Aging and the Role of Receptor-Interacting Protein Kinase
Esteban Díaz-Jara, Karla G Schwarz, Angelica Ríos-Gallardo, Camilo Toledo, Julio A Alcayaga, Felipe A Court, Rodrigo Del Rio.
Adv Exp Med Biol. 1427:195-201. doi: 10.1007/978-3-031-32371-3_21.
PUBLICATIONSNeuroDegenerationAGING
abril 19, 2023
Necroptosis inhibition counteracts axonal degeneration, cognitive decline and key hallmarks of aging, promoting brain rejuvenation.
Macarena S. Arrázola, Matías Lira, Gabriel Quiroz, Somya Iqbal, Samantha L Eaton, Rachel A Kline, Douglas J Lamont, Hernán Huerta, Gonzalo Ureta, Sebastián Bernales, J César Cárdenas, Waldo Cerpa,Thomas M. Wishart, Felipe A. Court
Aging Cell. Mar 27;e13814. doi: 10.1111/acel.13814. Online ahead of print.
PUBLICATIONSDataCNSNeuroDegeneration
agosto 29, 2022
An Optimized Comparative Proteomic Approach as a Tool in Neurodegenerative Disease Research
Rachel A. Kline, Lena Lößlein, Dominic Kurian, Judit Aguilar Martí, Samantha L. Eaton,
Felipe A. Court, Thomas H. Gillingwater, and Thomas M. Wishart
PUBLICATIONSDataNervous System FxCNSNeuroDegenerationAGING
agosto 8, 2022
Commentary on «PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons»
Macarena S. Arrázola, Court FA.
PMID: 35900426
PUBLICATIONSDataCNSNeuroDegenerationAGING
junio 3, 2022
Multiple events case–control study in a prospective cohort to identify systemic, cellular, and molecular biomarkers of obesity‑induced accelerated aging in 30‑years‑olds: the ObAGE study protocol
Correa‑Burrows P, Burrows R, Albala C, Court FA, Salech F, Sanhueza G and Gonzalez‑Billault C.
PMID: 35501766
PUBLICATIONSDataCNSNeuroDegenerationAGING
marzo 24, 2022
Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer’s disease
Natalia Salvadores, Ines Moreno‑Gonzalez, Nazaret Gamez, Gabriel Quiroz, Laura Vegas‑Gomez, Marcela Escandón, Sebastian Jimenez, Javier Vitorica, Antonia Gutierrez, Claudio Soto and Felipe A. Court.
PMID: 35264247
PUBLICATIONSBioRxivNeuroDegenerationAGING
noviembre 25, 2021
Necroptosis inhibition counteracts axonal degeneration, cognitive decline and key hallmarks of aging, promoting brain rejuvenation.
Macarena S. Arrázola, Matías Lira, Gabriel Quiroz, Somya Iqbal, Samantha L Eaton, Rachel A Kline, Douglas J Lamont, Hernán Huerta, Gonzalo Ureta, Sebastián Bernales, J César Cárdenas, Waldo Cerpa,Thomas M. Wishart, Felipe A. Court
bioRxiv doi: https://doi.org/10.1101/2021.11.10.468052
PUBLICATIONSDataCNSNeuroDegenerationAGING
octubre 7, 2021
Enhanced Activity of Exportin-1/CRM1 in Neurons Contributes to Autophagy Dysfunction and Senescent Features in Old Mouse Brain.
Gorostieta-Salas E, Moreno-Blas D, Gerónimo-Olvera C, Cisneros B, Court FA, Castro-Obregón S.
Oxid Med Cell Longev. 2021 Aug 13;2021:6682336. doi: 10.1155/2021/6682336. eCollection 2021.
PMID: 34434486
PUBLICATIONSReviewCNSNeuroDegenerationAGING
octubre 7, 2021
Dementia in Latin America: Paving the way toward a regional action plan.
Parra MA, Baez S, Sedeño L, Gonzalez Campo C, Santamaría-García H, Aprahamian I, Bertolucci PH, Bustin J, Camargos Bicalho MA, Cano-Gutierrez C, Caramelli P, Chaves MLF, Cogram P, Beber BC, Court FA, de Souza LC, Custodio N, Damian A, de la Cruz M, Diehl Rodriguez R, Brucki SMD, Fajersztajn L, Farías GA, De Felice FG, Ferrari R, de Oliveira FF, Ferreira ST, Ferretti C, Figueredo Balthazar ML, Ferreira Frota NA, Fuentes P, García AM, Garcia PJ, de Gobbi Porto FH, Duque Peñailillo L, Engler HW, Maier I, Mata IF, Gonzalez-Billault C, Lopez OL, Morelli L, Nitrini R, Quiroz YT, Guerrero Barragan A, Huepe D, Pio FJ, Suemoto CK, Kochhann R, Kochen S, Kumfor F, Lanata S, Miller B, Mansur LL, Hosogi ML, Lillo P, Llibre Guerra J, Lira D, Lopera F, Comas A, Avila-Funes JA, Sosa AL, Ramos C, Resende EPF, Snyder HM, Tarnanas I, Yokoyama J, Llibre J, Cardona JF, Possin K, Kosik KS, Montesinos R, Moguilner S, Solis PCL, Ferretti-Rebustini REL, Ramirez JM, Matallana D, Mbakile-Mahlanza L, Marques Ton AM, Tavares RM, Miotto EC, Muniz-Terrera G, Muñoz-Nevárez LA, Orozco D, Okada de Oliveira M, Piguet O, Pintado Caipa M, Piña Escudero SD, Schilling LP, Rodrigues Palmeira AL, Yassuda MS, Santacruz-Escudero JM, Serafim RB, Smid J, Slachevsky A, Serrano C, Soto-Añari M, Takada LT, Grinberg LT, Teixeira AL, Barbosa MT, Trépel D, Ibanez A.
Alzheimers Dement. 2021 Feb;17(2):295-313. doi: 10.1002/alz.12202. Epub 2020 Nov 20.
PMID: 33634602
PUBLICATIONSProtocolCNSNeuroDegenerationAGING
octubre 7, 2021
GERO Cohort Protocol, Chile, 2017-2022: Community-based Cohort of Functional Decline in Subjective Cognitive Complaint elderly.
Slachevsky A, Zitko P, Martínez-Pernía D, Forno G, Court FA, Lillo P, Villagra R, Duran-Aniotz C, Parrao T, Assar R, Orellana P, Toledo C, Rivera R, Ibañez A, Parra MA, González-Billault C, Amieva H, Thumala D.
BMC Geriatr. 2020 Nov 25;20(1):505. doi: 10.1186/s12877-020-01866-4.
PMID: 33238908
PUBLICATIONSReviewCNSNeuroDegenerationAGING
octubre 7, 2021
Axonal Degeneration in AD: The Contribution of Aβ and Tau.
Salvadores N, Gerónimo-Olvera C, Court FA.
Front Aging Neurosci. 2020 Oct 15;12:581767. doi: 10.3389/fnagi.2020.581767. eCollection 2020.
PMID: 33192476
PUBLICATIONSChapterProtocolPNSNeuroDegeneration
octubre 7, 2021
Ex Vivo Analysis of Axonal Degeneration Using Sciatic and Optic Nerve Preparations.
López-Leal R, Court FA.
Methods Mol Biol. 2020;2143:179-189. doi: 10.1007/978-1-0716-0585-1_14.
PMID: 32524481
PUBLICATIONSDataCNSNeuroDegeneration
octubre 7, 2021
Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates.
García-Huerta P, Troncoso-Escudero P, Wu D, Thiruvalluvan A, Cisternas-Olmedo M, Henríquez DR, Plate L, Chana-Cuevas P, Saquel C, Thielen P, Longo KA, Geddes BJ, Lederkremer GZ, Sharma N, Shenkman M, Naphade S, Sardi SP, Spichiger C, Richter HG, Court FA, Tshilenge KT, Ellerby LM, Wiseman RL, Gonzalez-Billault C, Bergink S, Vidal RL, Hetz C.
Acta Neuropathol. 2020 Nov;140(5):737-764. doi: 10.1007/s00401-020-02183-1. Epub 2020 Jul 8.
PMID: 32642868
PUBLICATIONSDataPNSNeuroDegeneration
octubre 7, 2021
Metformin protects from oxaliplatin induced peripheral neuropathy in rats.
Martinez NW, Sánchez A, Diaz P, Broekhuizen R, Godoy J, Mondaca S, Catenaccio A, Macanas P, Nervi B, Calvo M, Court FA.
Neurobiol Pain. 2020 May 22;8:100048. doi: 10.1016/j.ynpai.2020.100048. eCollection 2020 Aug-Dec.
PMID: 32490289
PUBLICATIONSReviewNeuroDegenerationAGING
octubre 7, 2021
The Necroptosis Pathway and Its Role in Age-Related Neurodegenerative Diseases: Will It Open Up New Therapeutic Avenues in the Next Decade?
Salvadores N, Court FA.
Expert Opin Ther Targets. 2020 Jul;24(7):679-693. doi: 10.1080/14728222.2020.1758668. Epub 2020 May 4
PMID: 32310729