PUBLICATIONSDataPNSCNSNeuroDegeneration
octubre 5, 2021
Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling.
Rojas F, Gonzalez D, Cortes N, Ampuero E, Hernández DE, Fritz E, Abarzua S, Martinez A, Elorza AA, Alvarez A, Court F, van Zundert B.
Front Cell Neurosci. 2015 Jun 9;9:203. doi: 10.3389/fncel.2015.00203. eCollection 2015.
PMID: 26106294
PUBLICATIONSDataPNSNeuroDegeneration
octubre 4, 2021
Calcium release from intra-axonal endoplasmic reticulum leads to axon degeneration through mitochondrial dysfunction.
Villegas R, Martinez NW, Lillo J, Pihan P, Hernandez D, Twiss JL, Court FA.
J Neurosci. 2014 May 21;34(21):7179-89. doi: 10.1523/JNEUROSCI.4784-13.2014.
PMID: 24849352
PUBLICATIONSDataPNSCNSNeuroDegeneration
octubre 4, 2021
Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons.
Castillo K, Nassif M, Valenzuela V, Rojas F, Matus S, Mercado G, Court FA, van Zundert B, Hetz C.
Autophagy. 2013 Sep;9(9):1308-20. doi: 10.4161/auto.25188. Epub 2013 Jun 6.
PMID: 23851366
PUBLICATIONSDataPNSNeuroDegeneration
octubre 4, 2021
Diapause formation and downregulation of Insulin-like signaling via DAF-16/FOXO delays axonal degeneration and neuronal loss.
Calixto A, Jara JS, Court FA.
PLoS Genet. 2012;8(12):e1003141. doi: 10.1371/journal.pgen.1003141. Epub 2012 Dec 27.
PMID: 23300463
PUBLICATIONSReviewPNSCNSNeuroDegeneration
octubre 4, 2021
Mitochondria as a central sensor for axonal degenerative stimuli.
Court FA, Coleman MP.
Trends Neurosci. 2012 Jun;35(6):364-72. doi: 10.1016/j.tins.2012.04.001. Epub 2012 May 11.
PMID: 22578891
PUBLICATIONSDataPNSCNSNeuroDegeneration
octubre 4, 2021
Axonal degeneration is mediated by the mitochondrial permeability transition pore.
Barrientos SA, Martinez NW, Yoo S, Jara JS, Zamorano S, Hetz C, Twiss JL, Alvarez J, Court FA.
J Neurosci. 2011 Jan 19;31(3):966-78. doi: 10.1523/JNEUROSCI.4065-10.2011.
PMID: 21248121
PUBLICATIONSDataNervous System FxPNSNeuroDegeneration
septiembre 30, 2021
Schwann cell to axon transfer of ribosomes: toward a novel understanding of the role of glia in the nervous system.
Court FA, Hendriks WT, MacGillavry HD, Alvarez J, van Minnen J.
J Neurosci. 2008 Oct 22;28(43):11024-9. doi: 10.1523/JNEUROSCI.2429-08.2008.
PMID: 18945910
PUBLICATIONSDataPNSNeuroDegeneration
septiembre 30, 2021
Remodeling of motor nerve terminals in demyelinating axons of periaxin-null mice.
Court FA, Brophy PJ, Ribchester RR.
Glia. 2008 Mar;56(4):471-9. doi: 10.1002/glia.20620.
PMID: 18205176
PUBLICATIONSDataPNSCNSNeuroDegeneration
septiembre 30, 2021
Progressive abnormalities in skeletal muscle and neuromuscular junctions of transgenic mice expressing the Huntington’s disease mutation.
Ribchester RR, Thomson D, Wood NI, Hinks T, Gillingwater TH, Wishart TM, Court FA, Morton AJ.
Eur J Neurosci. 2004 Dec;20(11):3092-114. doi: 10.1111/j.1460-9568.2004.03783.x.
PMID: 15579164
PUBLICATIONSDataPNSNeuroDegeneration
septiembre 30, 2021
Neurons expressing the highest levels of gamma-synuclein are unaffected by targeted inactivation of the gene.
Ninkina N, Papachroni K, Robertson DC, Schmidt O, Delaney L, O'Neill F, Court F, Rosenthal A, Fleetwood-Walker SM, Davies AM, Buchman VL.
Mol Cell Biol. 2003 Nov;23(22):8233-45. doi: 10.1128/MCB.23.22.8233-8245.2003.
PMID: 14585981
PUBLICATIONSDataPNSNeuroDegeneration
septiembre 30, 2021
Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene.
Mack TG, Reiner M, Beirowski B, Mi W, Emanuelli M, Wagner D, Thomson D, Gillingwater T, Court F, Conforti L, Fernando FS, Tarlton A, Andressen C, Addicks K, Magni G, Ribchester RR, Perry VH, Coleman MP.
Nat Neurosci. 2001 Dec;4(12):1199-206. doi: 10.1038/nn770.
PMID: 11770485