Felipe Court

Director, Center for Integrative Biology

I studied biology in Chile working as an undergraduate in the lab of Dr. Jaime Alvarez in local protein synthesis in axons. I then moved to Europe and obtained an MSc and later a Ph.D. at Edinburgh University working in the labs of Dr. Richard Ribchester and Dr. Peter Brophy. Holding an EMBO postdoctoral fellowship, I moved to the lab of Dr. Laura Feltri in Milano, Italy.

My research has been focused in studying the relationship between glial cells and neurons in different biological processes, including axonal degeneration, regeneration and intracellular transfer of cargoes. For this, we use models of axonal degeneration and regeneration in vivo and in vitro, including models of optic and sciatic nerve regeneration and spinal cord injury.

Universidad Mayor
Tel: +562 2328 1334

Génesis Vega

Postdoctoral fellow

Bachelor’s degree in Biochemistry at the Universidad Austral de Chile. PhD in Sciences with mention in cellular and molecular biology at the Universidad Austral de Chile carried out at CECs and University of Heidelberg. Studying the role of NAD+ imbalance in the activation of necrosome and dysfunction of mitochondrial metabolism in chemotherapy-induced axonal degeneration in aged peripheral neurons.

Nicole Letelier

Postdoctoral fellow

Biochemist and master in Biochemistry from University of Chile. PhD in Biomedicine by University of Barcelona with strong knowledge in immunology. My doctoral thesis focused on the mechanisms of LXR-mediated control of obesity-induced metaflammation and insulin-resistance.

Karina Girardi do Carmo

Postdoctoral fellow

Biologist, Ph.D., and MSc in Cell and Molecular Biology from Oswaldo Cruz Foundation (Fiocruz/RJ). Studying age-dependent decline of regenerative capacity in the peripheral nervous system. Mainly focusing on the contribution of metabolic profile of aging Schwann cells in senescence and particularly exploring the epithelial-mesenchymal transition (EMT) like process.

Andrés Fuentes

PhD Student

Biotechnologist and PhD in Integrative Genomics from the Mayor University, Chile. Currently working in the characterization and indiction of senescence over Schwann cells in the context of chronic denervation and aging. Aiming to assess the clinical impact of senescent Schwann cells over axonal regeneration in the peripheral nervous system after mechanical damage.

Francisco Muñoz

PhD Student

Biotechnologist from Universidad Mayor. PhD candidate in Neurobiology at the Center for Integrative Biology (CIB) from Universidad Mayor. Working on the regulating role of aging associated methylation upon mitochondrial stress through the mitochondrial unfolded protein response (UPRmt) and its impact on neurodegeneration and the functionality of the olfactoctory system using Drosophila as a model.

Felipe Véliz Valverde

PhD Student

Msc Neuroscience. Neurobiology PhD student at Universidad Mayor. I´m interested in understand the  effects of exercise in the aging brain. Skeletal muscle can crosstalk with the brain by myokines, triggering neuroprotective effects.  The aim question of my work is whether some myokines can protects against axonal degeneration by a necroptotic-dependent mechanism.

Enso Torres

PhD Student

Chemical Engineer from Technological University of Havana ”José Antonio Echevarría” with experience in chemical synthesis of peptides, mass spectrometry and proteomics tools. I’m currently working on necroptosis and inflammation in aging and its relationship with oxidative stress in mitochondria.

David Necuñir

Research Assitant

Biotechnology Engineer and Master from Universidad Nacional Andrés Bello, Santiago de Chile. I’m currently working on the role of necroptosis in axonal degeneration in mesencephalic neurons primary culture, RNA transference and glial cells-neurons communication mediated by exosomes using Schwann cells and evaluating regeneration of peripheral neurons.

Pedro Briceño

Research Assistant

Biologist and master of Biological sciences from University of Chile. In a model of chemotherapy-induced peripheral neuropathy, I’m investigating an axonal degeneration mechanism involving necroptosis activation. I’m focusing on two events that influence this process: the role of a decrease in the basal NAD+ pool and mitochondrial metabolism dysfunction.

José Ángel Landa

Lab Manager

Business Manager from Universidad Privada del Estado de Morelos, México.

Iasnaia Ferrer

Assistant

Bachelor degree in Translation and Interpreting student at the Universidad de las Americas, Santiago de Chile.

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POSITIONS

Past members

  • Eileen Collyer – Postdoc, UCSD
  • Sebastián Barrientos – Bachelor in Biology, Ph,D
  • Juan S. Jara – Universite de Paris, Faculte des Sciences
  • David Cajas – 4th year Biochemistry student at Catholic
  • Diego Reginensi – MSc in Neuroscience
  • Rosario Villegas – Postdoc, PUC
  • Valeria Godoy – Postdoc
  • Vania Macias – Pregrado Student
  • Nicolas Martinez – Phd Student
  • Diego Hernández – PhD Student
  • Mónica Perez – Electron Microscopy
  • Claudia Carcamo – Research Assistant
  • Mario Sanhueza – Postdoctoral fellow
  • Mariela Araya – Postdoctoral fellow
  • Luis Valenzuela – Postdoctoral fellow
  • Cristian Valdebenito – Undergraduate Student
  • Pamela Rojas – Biochemistry student PUC
  • Javiera Villar – Biochemistry student at U. de Chile
  • Joaquín Cerca – Biochemist
  • Bruno Cisternas – MSc in Neuroscience
  • Cheryg Chavez – Lab. Manager
  • Álvaro Sánchez – Postdoc
  • Frederic Picou – Postdoc
  • Vicente Figueroa – Pregrado Student
  • Jaime Álvarez – Medical Doctor
  • Paula Diaz – Research Assistant
  • Claudia Orellana-Tavra – Postdoctoral fellow

     

  • Angelica Jaramillo – Research Assistant
  • Cristian Saquel – Research Assistant
  • Valentina Haro – Postdoctoral fellow
  • Gabriela Caceres – Research Assistant
  • Gerard Ill-Raga – Postdoctoral, Brazil
  • Alejandra López – P. Universidad Catolica de Chile
  • Vicente Valenzuela – MSc in Biotechnology.
  • Hugo Penailillo – Undergraduate student, Biology
  • Beatriz Díaz – Biologist
  • Fernanda Espinoza – Lab Manager
  • Constanza Miller – Lab Proyect
  • Alfredo Araneda – Pregrado Student
  • Carolina Chávez – Lab Manager
  • Cristian de Gregorio – Postdoctoral fellow
  • Maritza Oñate – PhD
  • Rodrigo López-Leal – Postdoctoral fellow
  • Alejandra Palma – Research Assistant
  • Victor Cueva – Research Assistant
  • Romina Catalán – Research Assistant
  • Natalia Salvadores – Postdoctoral fellow
  • Sergio Benites – Postdoctoral fellow
  • Alejandra Catenaccio – Research fellow
  • Macarena Arrazola – Postdoctoral fellow
  • Francisco Moya – Postdoctoral fellow
  • Cristian Geronimo – Postdoctoral fellow