PUBLICATIONSReviewPNSCNSNeuroDegenerationAGING
octubre 5, 2021
Mitochondria and Calcium Regulation as Basis of Neurodegeneration Associated With Aging.
Müller M, Ahumada-Castro U, Sanhueza M, Gonzalez-Billault C, Court FA, Cárdenas C.
Front Neurosci. 2018 Jul 13;12:470. doi: 10.3389/fnins.2018.00470. eCollection 2018.
PMID: 30057523
PUBLICATIONSDataPNSCNSNeuroDegeneration
octubre 5, 2021
The inhibition of CTGF/CCN2 activity improves muscle and locomotor function in a murine ALS model.
Gonzalez D, Rebolledo DL, Correa LM, Court FA, Cerpa W, Lipson KE, van Zundert B, Brandan E.
Hum Mol Genet. 2018 Aug 15;27(16):2913-2926. doi: 10.1093/hmg/ddy204.
PMID: 29860398
PUBLICATIONSDataPNSNeuroDegeneration
octubre 5, 2021
Molecular analysis of axonal-intrinsic and glial-associated co-regulation of axon degeneration.
Catenaccio A, Llavero Hurtado M, Diaz P, Lamont DJ, Wishart TM, Court FA.
Cell Death Dis. 2017 Nov 9;8(11):e3166. doi: 10.1038/cddis.2017.489.
PMID: 29120410
PUBLICATIONSReviewNervous System FxPNS
octubre 5, 2021
Schwann Cell and Axon: An Interlaced Unit-From Action Potential to Phenotype Expression.
Court FA, Alvarez J.
Adv Exp Med Biol. 2016;949:183-201. doi: 10.1007/978-3-319-40764-7_9.
PMID: 27714690
PUBLICATIONSDataPNSNeuroRegeneration
octubre 5, 2021
Activation of the unfolded protein response promotes axonal regeneration after peripheral nerve injury.
Oñate M, Catenaccio A, Martínez G, Armentano D, Parsons G, Kerr B, Hetz C, Court FA.
Sci Rep. 2016 Feb 24;6:21709. doi: 10.1038/srep21709.
PMID: 26906090
PUBLICATIONSDataNervous System FxPNS
octubre 5, 2021
Axons Provide the Secretory Machinery for Trafficking of Voltage-Gated Sodium Channels in Peripheral Nerve.
González C, Cánovas J, Fresno J, Couve E, Court FA, Couve A.
Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1823-8. doi: 10.1073/pnas.1514943113. Epub 2016 Feb 2.
PMID: 26839409
PUBLICATIONSDataPNSNeuroRegeneration
octubre 5, 2021
Schwann Cell Exosomes Mediate Neuron–Glia Communication and Enhance Axonal Regeneration.
Lopez-Leal R, Court FA.
Cell Mol Neurobiol. 2016 Apr;36(3):429-36. doi: 10.1007/s10571-015-0314-3. Epub 2016 Mar 18.
PMID: 26993502
PUBLICATIONSDataPNSNeuroDegeneration
octubre 5, 2021
Altered potassium channel distribution and composition in myelinated axons suppresses hyperexcitability following injury.
Calvo M, Richards N, Schmid AB, Barroso A, Zhu L, Ivulic D, Zhu N, Anwandter P, Bhat MA, Court FA, McMahon SB, Bennett DL.
Elife. 2016 Apr 19;5:e12661. doi: 10.7554/eLife.12661.
PMID: 27033551
PUBLICATIONSReviewPNSCNSNeuroDegenerationNeuroRegeneration
octubre 5, 2021
Injury to the nervous system: A look into the ER.
Valenzuela V, Oñate M, Hetz C, Court FA.
Brain Res. 2016 Oct 1;1648(Pt B):617-625. doi: 10.1016/j.brainres.2016.04.053. Epub 2016 Apr 23.
PMID: 27117870
PUBLICATIONSReviewPNSNeuroRegeneration
octubre 5, 2021
Bursting the unfolded protein response accelerates axonal regeneration.
Oñate M, Court FA, Hetz C.
Neural Regen Res. 2016 Jun;11(6):892-3. doi: 10.4103/1673-5374.184453.
PMID: 27482204
PUBLICATIONSDataPNSCNSNeuroDegeneration
octubre 5, 2021
Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling.
Rojas F, Gonzalez D, Cortes N, Ampuero E, Hernández DE, Fritz E, Abarzua S, Martinez A, Elorza AA, Alvarez A, Court F, van Zundert B.
Front Cell Neurosci. 2015 Jun 9;9:203. doi: 10.3389/fncel.2015.00203. eCollection 2015.
PMID: 26106294
PUBLICATIONSDataPNSNeuroRegeneration
octubre 5, 2021
Functional Role of the Disulfide Isomerase ERp57 in Axonal Regeneration.
Kerr B, Court FA, Hetz C.
PLoS One. 2015 Sep 11;10(9):e0136620. doi: 10.1371/journal.pone.0136620. eCollection 2015.
PMID: 26361352
PUBLICATIONSDataPNSNeuroRegeneration
octubre 5, 2021
ApoER2 and Reelin are expressed in regenerating peripheral nerve and regulate Schwann cell migration by activating the Rac1 GEF protein, Tiam1.
Pasten C, Cerda J, Jausoro I, Court FA, Cáceres A, Marzolo MP.
Mol Cell Neurosci. 2015 Nov;69:1-11. doi: 10.1016/j.mcn.2015.09.004. Epub 2015 Sep 16.
PMID: 26386179
PUBLICATIONSDataNervous System FxPNSCNS
octubre 4, 2021
The p75 neurotrophin receptor evades the endolysosomal route, favouring multivesicular bodies specialised for exosomal release in neuronal cells.
Escudero CA, Lazo OM, Galleguillos C, Parraguez JI, Lopez-Verrilli MA, Cabeza C, Leon L, Saeed U, Retamal C, Gonzalez A, Marzolo MP, Carter BD, Court FA, Bronfman FC.
J Cell Sci. 2014 May 1;127(Pt 9):1966-79. doi: 10.1242/jcs.141754. Epub 2014 Feb 25.
PMID: 24569882
PUBLICATIONSDataPNSNeuroDegeneration
octubre 4, 2021
Calcium release from intra-axonal endoplasmic reticulum leads to axon degeneration through mitochondrial dysfunction.
Villegas R, Martinez NW, Lillo J, Pihan P, Hernandez D, Twiss JL, Court FA.
J Neurosci. 2014 May 21;34(21):7179-89. doi: 10.1523/JNEUROSCI.4784-13.2014.
PMID: 24849352