PUBLICATIONSDataPNSCNSNeuroDegeneration
octubre 5, 2021
Axonal degeneration is mediated by necroptosis activation.
Arrázola MS, Saquel C, Catalán RJ, Barrientos SA, Hernandez DE, Martínez NW, Catenaccio A, Court FA.
J Neurosci. 2019 May 15;39(20):3832-3844. doi: 10.1523/JNEUROSCI.0881-18.2019. Epub 2019 Mar 8.
PMID: 30850513
PUBLICATIONSDataPNSNeuroDegeneration
octubre 5, 2021
A dual role for Integrin α6β4 in modulating Hereditary Neuropathy with liability to Pressure Palsies.
Poitelon Y, Matafora V, Silvestri N, Zambroni D, McGarry C, Serghany N, Rush T, Vizzuso D, Court FA, Bachi A, Wrabetz L, Feltri ML.
J Neurochem. 2018 May;145(3):245-257. doi: 10.1111/jnc.14295. Epub 2018 Feb 13.
PMID: 29315582
octubre 5, 2021
IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A.
Urra H, Henriquez DR, Cánovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, Molina E, Hazari YM, Limia CM, Alvarez-Rojas S, Figueroa R, Vidal RL, Rodriguez DA, Rivera CA, Court FA, Couve A, Qi L, Chevet E, Akai R, Iwawaki T, Concha ML, Glavic Á, Gonzalez-Billault C, Hetz C.
Nat Cell Biol. 2018 Aug;20(8):942-953. doi: 10.1038/s41556-018-0141-0. Epub 2018 Jul 16.
PMID: 30013108
PUBLICATIONSDataPNSCNSNeuroDegeneration
octubre 5, 2021
The inhibition of CTGF/CCN2 activity improves muscle and locomotor function in a murine ALS model.
Gonzalez D, Rebolledo DL, Correa LM, Court FA, Cerpa W, Lipson KE, van Zundert B, Brandan E.
Hum Mol Genet. 2018 Aug 15;27(16):2913-2926. doi: 10.1093/hmg/ddy204.
PMID: 29860398
PUBLICATIONSDataCNSNeuroDegeneration
octubre 5, 2021
Axonal degeneration induced by glutamate excitotoxicity is mediated by necroptosis.
Hernández DE, Salvadores NA, Moya-Alvarado G, Catalán RJ, Bronfman FC, Court FA.
J Cell Sci. 2018 Nov 19;131(22):jcs214684. doi: 10.1242/jcs.214684.
PMID: 30333135
octubre 5, 2021
Herpes Simplex Virus Type 1 Neuronal Infection Perturbs Golgi Apparatus Integrity through Activation of Src Tyrosine Kinase and Dyn-2 GTPase.
Martin C, Leyton L, Hott M, Arancibia Y, Spichiger C, McNiven MA, Court FA, Concha MI, Burgos PV, Otth C
Front Cell Infect Microbiol. 2017 Aug 22;7:371. doi: 10.3389/fcimb.2017.00371. eCollection 2017.
PMID: 28879169
octubre 5, 2021
Resistance of leukemia cells to cytarabine chemotherapy is mediated by bone marrow stroma, involves cell-surface equilibrative nucleoside transporter-1 removal and correlates with patient outcome.
Macanas-Pirard P, Broekhuizen R, González A, Oyanadel C, Ernst D, García P, Montecinos VP, Court F, Ocqueteau M, Ramirez P, Nervi B.
Oncotarget. 2017 Apr 4;8(14):23073-23086. doi: 10.18632/oncotarget.14981.
PMID: 28160570
PUBLICATIONSDataCNSNeuroDegeneration
octubre 5, 2021
Disulfide cross-linked multimers of TDP-43 and spinal motoneuron loss in a TDP-43A315T ALS/FTD mouse model.
Bargsted L, Medinas DB, Martínez Traub F, Rozas P, Muñoz N, Nassif M, Jerez C, Catenaccio A, Court FA, Hetz C, Matus S.
Sci Rep. 2017 Oct 27;7(1):14266. doi: 10.1038/s41598-017-14399-5.
PMID: 29079747
PUBLICATIONSDataPNSNeuroDegeneration
octubre 5, 2021
Molecular analysis of axonal-intrinsic and glial-associated co-regulation of axon degeneration.
Catenaccio A, Llavero Hurtado M, Diaz P, Lamont DJ, Wishart TM, Court FA.
Cell Death Dis. 2017 Nov 9;8(11):e3166. doi: 10.1038/cddis.2017.489.
PMID: 29120410
octubre 5, 2021
BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response.
Castillo K, Rojas-Rivera D, Lisbona F, Caballero B, Nassif M, Court FA, Schuck S, Ibar C, Walter P, Sierralta J, Glavic A, Hetz C.
EMBO J. 2017 Jun 1;36(11):1640. doi: 10.15252/embj.201797020.
PMID: 28572284
PUBLICATIONSDataPNSNeuroRegeneration
octubre 5, 2021
Activation of the unfolded protein response promotes axonal regeneration after peripheral nerve injury.
Oñate M, Catenaccio A, Martínez G, Armentano D, Parsons G, Kerr B, Hetz C, Court FA.
Sci Rep. 2016 Feb 24;6:21709. doi: 10.1038/srep21709.
PMID: 26906090
PUBLICATIONSDataNervous System FxPNS
octubre 5, 2021
Axons Provide the Secretory Machinery for Trafficking of Voltage-Gated Sodium Channels in Peripheral Nerve.
González C, Cánovas J, Fresno J, Couve E, Court FA, Couve A.
Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1823-8. doi: 10.1073/pnas.1514943113. Epub 2016 Feb 2.
PMID: 26839409
PUBLICATIONSDataPNSNeuroRegeneration
octubre 5, 2021
Schwann Cell Exosomes Mediate Neuron–Glia Communication and Enhance Axonal Regeneration.
Lopez-Leal R, Court FA.
Cell Mol Neurobiol. 2016 Apr;36(3):429-36. doi: 10.1007/s10571-015-0314-3. Epub 2016 Mar 18.
PMID: 26993502
PUBLICATIONSDataPNSNeuroDegeneration
octubre 5, 2021
Altered potassium channel distribution and composition in myelinated axons suppresses hyperexcitability following injury.
Calvo M, Richards N, Schmid AB, Barroso A, Zhu L, Ivulic D, Zhu N, Anwandter P, Bhat MA, Court FA, McMahon SB, Bennett DL.
Elife. 2016 Apr 19;5:e12661. doi: 10.7554/eLife.12661.
PMID: 27033551
PUBLICATIONSDataCNSNeuroDegeneration
octubre 5, 2021
Microtubule-associated protein 1B (MAP1B)-deficient neurons show structural presynaptic deficiencies in vitro and altered presynaptic physiology.
Bodaleo FJ, Montenegro-Venegas C, Henríquez DR, Court FA, Gonzalez-Billault C.
Sci Rep. 2016 Jul 18;6:30069. doi: 10.1038/srep30069.
PMID: 27425640