PUBLICATIONSNeuroDegenerationAGING
septiembre 5, 2023
Carotid Body-Mediated Chemoreflex Function in Aging and the Role of Receptor-Interacting Protein Kinase
Esteban Díaz-Jara, Karla G Schwarz, Angelica Ríos-Gallardo, Camilo Toledo, Julio A Alcayaga, Felipe A Court, Rodrigo Del Rio.
Adv Exp Med Biol. 1427:195-201. doi: 10.1007/978-3-031-32371-3_21.
PUBLICATIONSNeuroDegenerationAGING
abril 19, 2023
Necroptosis inhibition counteracts axonal degeneration, cognitive decline and key hallmarks of aging, promoting brain rejuvenation.
Macarena S. Arrázola, Matías Lira, Gabriel Quiroz, Somya Iqbal, Samantha L Eaton, Rachel A Kline, Douglas J Lamont, Hernán Huerta, Gonzalo Ureta, Sebastián Bernales, J César Cárdenas, Waldo Cerpa,Thomas M. Wishart, Felipe A. Court
Aging Cell. Mar 27;e13814. doi: 10.1111/acel.13814. Online ahead of print.
PUBLICATIONSNeuroRegenerationAGING
enero 25, 2023
Senescent Schwann cells induced by aging and chronic denervation impair axonal regeneration after peripheral nerve injury
Andrés Fuentes-Flores, Cristian Geronimo-Olvera, David Ñecuñir, Sandip Kumar Patel, Joanna Bons, Megan C Wright, Daniel Geschwind, Ahmet Hoke, Jose A. Gomez-Sanchez, Birgit Schilling, Judith Campisi, Felipe A. Court
PUBLICATIONSDataNervous System FxCNSNeuroDegenerationAGING
agosto 8, 2022
Commentary on «PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons»
Macarena S. Arrázola, Court FA.
PMID: 35900426
PUBLICATIONSDataCNSNeuroDegenerationAGING
junio 3, 2022
Multiple events case–control study in a prospective cohort to identify systemic, cellular, and molecular biomarkers of obesity‑induced accelerated aging in 30‑years‑olds: the ObAGE study protocol
Correa‑Burrows P, Burrows R, Albala C, Court FA, Salech F, Sanhueza G and Gonzalez‑Billault C.
PMID: 35501766
PUBLICATIONSDataCNSNeuroDegenerationAGING
marzo 24, 2022
Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer’s disease
Natalia Salvadores, Ines Moreno‑Gonzalez, Nazaret Gamez, Gabriel Quiroz, Laura Vegas‑Gomez, Marcela Escandón, Sebastian Jimenez, Javier Vitorica, Antonia Gutierrez, Claudio Soto and Felipe A. Court.
PMID: 35264247
PUBLICATIONSBioRxivNeuroDegenerationAGING
noviembre 25, 2021
Necroptosis inhibition counteracts axonal degeneration, cognitive decline and key hallmarks of aging, promoting brain rejuvenation.
Macarena S. Arrázola, Matías Lira, Gabriel Quiroz, Somya Iqbal, Samantha L Eaton, Rachel A Kline, Douglas J Lamont, Hernán Huerta, Gonzalo Ureta, Sebastián Bernales, J César Cárdenas, Waldo Cerpa,Thomas M. Wishart, Felipe A. Court
bioRxiv doi: https://doi.org/10.1101/2021.11.10.468052
PUBLICATIONSDataCNSNeuroDegenerationAGING
octubre 7, 2021
Enhanced Activity of Exportin-1/CRM1 in Neurons Contributes to Autophagy Dysfunction and Senescent Features in Old Mouse Brain.
Gorostieta-Salas E, Moreno-Blas D, Gerónimo-Olvera C, Cisneros B, Court FA, Castro-Obregón S.
Oxid Med Cell Longev. 2021 Aug 13;2021:6682336. doi: 10.1155/2021/6682336. eCollection 2021.
PMID: 34434486
PUBLICATIONSReviewCNSNeuroDegenerationAGING
octubre 7, 2021
Dementia in Latin America: Paving the way toward a regional action plan.
Parra MA, Baez S, Sedeño L, Gonzalez Campo C, Santamaría-García H, Aprahamian I, Bertolucci PH, Bustin J, Camargos Bicalho MA, Cano-Gutierrez C, Caramelli P, Chaves MLF, Cogram P, Beber BC, Court FA, de Souza LC, Custodio N, Damian A, de la Cruz M, Diehl Rodriguez R, Brucki SMD, Fajersztajn L, Farías GA, De Felice FG, Ferrari R, de Oliveira FF, Ferreira ST, Ferretti C, Figueredo Balthazar ML, Ferreira Frota NA, Fuentes P, García AM, Garcia PJ, de Gobbi Porto FH, Duque Peñailillo L, Engler HW, Maier I, Mata IF, Gonzalez-Billault C, Lopez OL, Morelli L, Nitrini R, Quiroz YT, Guerrero Barragan A, Huepe D, Pio FJ, Suemoto CK, Kochhann R, Kochen S, Kumfor F, Lanata S, Miller B, Mansur LL, Hosogi ML, Lillo P, Llibre Guerra J, Lira D, Lopera F, Comas A, Avila-Funes JA, Sosa AL, Ramos C, Resende EPF, Snyder HM, Tarnanas I, Yokoyama J, Llibre J, Cardona JF, Possin K, Kosik KS, Montesinos R, Moguilner S, Solis PCL, Ferretti-Rebustini REL, Ramirez JM, Matallana D, Mbakile-Mahlanza L, Marques Ton AM, Tavares RM, Miotto EC, Muniz-Terrera G, Muñoz-Nevárez LA, Orozco D, Okada de Oliveira M, Piguet O, Pintado Caipa M, Piña Escudero SD, Schilling LP, Rodrigues Palmeira AL, Yassuda MS, Santacruz-Escudero JM, Serafim RB, Smid J, Slachevsky A, Serrano C, Soto-Añari M, Takada LT, Grinberg LT, Teixeira AL, Barbosa MT, Trépel D, Ibanez A.
Alzheimers Dement. 2021 Feb;17(2):295-313. doi: 10.1002/alz.12202. Epub 2020 Nov 20.
PMID: 33634602
PUBLICATIONSProtocolCNSNeuroDegenerationAGING
octubre 7, 2021
GERO Cohort Protocol, Chile, 2017-2022: Community-based Cohort of Functional Decline in Subjective Cognitive Complaint elderly.
Slachevsky A, Zitko P, Martínez-Pernía D, Forno G, Court FA, Lillo P, Villagra R, Duran-Aniotz C, Parrao T, Assar R, Orellana P, Toledo C, Rivera R, Ibañez A, Parra MA, González-Billault C, Amieva H, Thumala D.
BMC Geriatr. 2020 Nov 25;20(1):505. doi: 10.1186/s12877-020-01866-4.
PMID: 33238908
PUBLICATIONSReviewCNSNeuroDegenerationAGING
octubre 7, 2021
Axonal Degeneration in AD: The Contribution of Aβ and Tau.
Salvadores N, Gerónimo-Olvera C, Court FA.
Front Aging Neurosci. 2020 Oct 15;12:581767. doi: 10.3389/fnagi.2020.581767. eCollection 2020.
PMID: 33192476
PUBLICATIONSReviewNeuroDegenerationAGING
octubre 7, 2021
The Necroptosis Pathway and Its Role in Age-Related Neurodegenerative Diseases: Will It Open Up New Therapeutic Avenues in the Next Decade?
Salvadores N, Court FA.
Expert Opin Ther Targets. 2020 Jul;24(7):679-693. doi: 10.1080/14728222.2020.1758668. Epub 2020 May 4
PMID: 32310729
PUBLICATIONSDataCNSNeuroDegenerationAGING
octubre 7, 2021
The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease.
Oñate M, Catenaccio A, Salvadores N, Saquel C, Martinez A, Moreno-Gonzalez I, Gamez N, Soto P, Soto C, Hetz C, Court FA.
Cell Death Differ. 2020 Apr;27(4):1169-1185. doi: 10.1038/s41418-019-0408-4. Epub 2019 Oct 7.
PMID: 31591470
PUBLICATIONSReviewPNSCNSNeuroDegenerationAGING
octubre 5, 2021
Mitochondria and Calcium Regulation as Basis of Neurodegeneration Associated With Aging.
Müller M, Ahumada-Castro U, Sanhueza M, Gonzalez-Billault C, Court FA, Cárdenas C.
Front Neurosci. 2018 Jul 13;12:470. doi: 10.3389/fnins.2018.00470. eCollection 2018.
PMID: 30057523
PUBLICATIONSReviewNeuroDegenerationAGING
octubre 5, 2021
Axonal Degeneration during Aging and Its Functional Role in Neurodegenerative Disorders.
Salvadores N, Sanhueza M, Manque P, Court FA.
Front Neurosci. 2017 Sep 4;11:451. doi: 10.3389/fnins.2017.00451. eCollection 2017.
PMID: 28928628