PUBLICATIONSDataPNSNeuroRegeneration
septiembre 26, 2022
Neuronal activity-dependent ATP enhances the pro-growth effect of repair Schwann cell extracellular vesicles by increasing their miRNA-21 loading
Cristian Saquel, Romina J. Catalan, Rodrigo Lopez-Leal, Ramon A. Ramirez, David Necuñir, Ursula Wyneken, Christophe Lamaze and Felipe A. Court
PUBLICATIONSDataCNSNeuroDegeneration
agosto 29, 2022
An Optimized Comparative Proteomic Approach as a Tool in Neurodegenerative Disease Research
Rachel A. Kline, Lena Lößlein, Dominic Kurian, Judit Aguilar Martí, Samantha L. Eaton,
Felipe A. Court, Thomas H. Gillingwater, and Thomas M. Wishart
PUBLICATIONSDataNervous System FxCNSNeuroDegenerationAGING
agosto 8, 2022
Commentary on «PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons»
Macarena S. Arrázola, Court FA.
PMID: 35900426
PUBLICATIONSDataCNSNeuroDegenerationAGING
junio 3, 2022
Multiple events case–control study in a prospective cohort to identify systemic, cellular, and molecular biomarkers of obesity‑induced accelerated aging in 30‑years‑olds: the ObAGE study protocol
Correa‑Burrows P, Burrows R, Albala C, Court FA, Salech F, Sanhueza G and Gonzalez‑Billault C.
PMID: 35501766
PUBLICATIONSDataCNSNeuroDegenerationAGING
marzo 24, 2022
Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer’s disease
Natalia Salvadores, Ines Moreno‑Gonzalez, Nazaret Gamez, Gabriel Quiroz, Laura Vegas‑Gomez, Marcela Escandón, Sebastian Jimenez, Javier Vitorica, Antonia Gutierrez, Claudio Soto and Felipe A. Court.
PMID: 35264247
PUBLICATIONSDataCNSNeuroDegenerationAGING
octubre 7, 2021
Enhanced Activity of Exportin-1/CRM1 in Neurons Contributes to Autophagy Dysfunction and Senescent Features in Old Mouse Brain.
Gorostieta-Salas E, Moreno-Blas D, Gerónimo-Olvera C, Cisneros B, Court FA, Castro-Obregón S.
Oxid Med Cell Longev. 2021 Aug 13;2021:6682336. doi: 10.1155/2021/6682336. eCollection 2021.
PMID: 34434486
PUBLICATIONSDataCNSNeuroDegeneration
octubre 7, 2021
Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates.
García-Huerta P, Troncoso-Escudero P, Wu D, Thiruvalluvan A, Cisternas-Olmedo M, Henríquez DR, Plate L, Chana-Cuevas P, Saquel C, Thielen P, Longo KA, Geddes BJ, Lederkremer GZ, Sharma N, Shenkman M, Naphade S, Sardi SP, Spichiger C, Richter HG, Court FA, Tshilenge KT, Ellerby LM, Wiseman RL, Gonzalez-Billault C, Bergink S, Vidal RL, Hetz C.
Acta Neuropathol. 2020 Nov;140(5):737-764. doi: 10.1007/s00401-020-02183-1. Epub 2020 Jul 8.
PMID: 32642868
PUBLICATIONSDataPNSNeuroRegeneration
octubre 7, 2021
Collateral Sprouting of Peripheral Sensory Neurons Exhibits a Unique Transcriptomic Profile.
Lemaitre D, Hurtado ML, De Gregorio C, Oñate M, Martínez G, Catenaccio A, Wishart TM, Court FA.
Mol Neurobiol. 2020 Oct;57(10):4232-4249. doi: 10.1007/s12035-020-01986-3. Epub 2020 Jul 21.
PMID: 32696431
PUBLICATIONSDataPNSNeuroDegeneration
octubre 7, 2021
Metformin protects from oxaliplatin induced peripheral neuropathy in rats.
Martinez NW, Sánchez A, Diaz P, Broekhuizen R, Godoy J, Mondaca S, Catenaccio A, Macanas P, Nervi B, Calvo M, Court FA.
Neurobiol Pain. 2020 May 22;8:100048. doi: 10.1016/j.ynpai.2020.100048. eCollection 2020 Aug-Dec.
PMID: 32490289
PUBLICATIONSDataNervous System FxPNSNeuroRegeneration
octubre 7, 2021
Schwann Cell Reprogramming Into Repair Cells Increases Exosome-Loaded miRNA-21 Promoting Axonal Growth.
López-Leal R, Díaz-Viraqué F, Catalán RJ, Saquel C, Enright A, Iraola G, Court FA.
J Cell Sci. 2020 Jun 15;133(12):jcs239004. doi: 10.1242/jcs.239004.
PMID: 32409566
PUBLICATIONSDataCNSNeuroDegenerationAGING
octubre 7, 2021
The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease.
Oñate M, Catenaccio A, Salvadores N, Saquel C, Martinez A, Moreno-Gonzalez I, Gamez N, Soto P, Soto C, Hetz C, Court FA.
Cell Death Differ. 2020 Apr;27(4):1169-1185. doi: 10.1038/s41418-019-0408-4. Epub 2019 Oct 7.
PMID: 31591470
PUBLICATIONSDataNervous System FxPNS
octubre 7, 2021
The p75NTR neurotrophin receptor is required to organize the mature neuromuscular synapse by regulating synaptic vesicle availability.
Pérez V, Bermedo-Garcia F, Zelada D, Court FA, Pérez MÁ, Fuenzalida M, Ábrigo J, Cabello-Verrugio C, Moya-Alvarado G, Tapia JC, Valenzuela V, Hetz C, Bronfman FC, Henríquez JP.
Acta Neuropathol Commun. 2019 Sep 12;7(1):147. doi: 10.1186/s40478-019-0802-7.
PMID: 31514753
PUBLICATIONSDataNervous System FxPNS
octubre 7, 2021
c-Jun N-terminal kinase (JNK)-dependent internalization and Rab5-dependent endocytic sorting mediate long-distance retrograde neuronal death induced by axonal BDNF-p75 signaling.
Escudero CA, Cabeza C, Moya-Alvarado G, Maloney MT, Flores CM, Wu C, Court FA, Mobley WC, Bronfman FC.
Sci Rep. 2019 Apr 15;9(1):6070. doi: 10.1038/s41598-019-42420-6.
PMID: 30988348
octubre 7, 2021
Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.
Carreras-Sureda A, Jaña F, Urra H, Durand S, Mortenson DE, Sagredo A, Bustos G, Hazari Y, Ramos-Fernández E, Sassano ML, Pihán P, van Vliet AR, González-Quiroz M, Torres AK, Tapia-Rojas C, Kerkhofs M, Vicente R, Kaufman RJ, Inestrosa NC, Gonzalez-Billault C, Wiseman RL, Agostinis P, Bultynck G, Court FA, Kroemer G, Cárdenas JC, Hetz C.
Nat Cell Biol. 2019 Jun;21(6):755-767. doi: 10.1038/s41556-019-0329-y. Epub 2019 May 20.
PMID: 31110288
PUBLICATIONSDataPNSNeuroDegeneration
octubre 5, 2021
Altered mitochondrial bioenergetics are responsible for the delay in Wallerian degeneration observed in neonatal mice.
Kline RA, Dissanayake KN, Hurtado ML, Martínez NW, Ahl A, Mole AJ, Lamont DJ, Court FA, Ribchester RR, Wishart TM, Murray LM.
Neurobiol Dis. 2019 Oct;130:104496. doi: 10.1016/j.nbd.2019.104496. Epub 2019 Jun 6.
PMID: 31176719